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Article

Functional polymorphisms of the TET1 gene increase the risk of neuroblastoma in Chinese children.

Journal of cellular and molecular medicine - 1 Aug 2023

Chang Jiaming, Lin Lei, Zhou Chunlei, Zhang Xinxin, Yang Tianyou, Wu Haiyan, Zou Yan, He Jing

Abstract excerpt

Common genetic mutations are absent in neuroblastoma, one of the most common childhood tumours. As a demethylase of 5-methylcytosine (m5C) modification, TET1 plays an important role in tumourigenesis and differentiation. However, the association between TET1 gene polymorphisms and susceptibility to neuroblastoma has not been reported. Three TET1 gene polymorphisms (rs16925541 A > G, rs3998860 G > A and rs12781492...

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Identifiers

PMID: 37347215
DOI: 10.1111/jcmm.17820
PMCID: PMC10399530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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