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Article

Sex differences of the shared genetic landscapes between type 2 diabetes and peripheral artery disease in East Asians and Europeans.

Human genetics - 1 Jul 2023

Lu Zhiya, Zhang Haoyang, Yang Yuanhao, Zhao Huiying

Abstract excerpt

Type 2 diabetes (T2D) is a critical risk factor for peripheral artery disease (PAD). However, the sex differences in genetic basis, causality, and underlying mechanisms of the two diseases are still unclear. Using sex-stratified and ethnic-based GWAS summary, we explored the genetic correlation and causal relationship between T2D and PAD in both ethnicities and sexes by linkage disequilibrium score regression,...

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Share to Diabetes Mellitus, Type 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37341850
DOI: 10.1007/s00439-023-02573-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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