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Article

Genetic evidence for a causal relationship between type 2 diabetes and peripheral artery disease in both Europeans and East Asians.

BMC medicine - 31 Aug 2022

Xiu Xuehao, Zhang Haoyang, Xue Angli, Cooper David N, Yan Li, Yang Yuedong, Yang Yuanhao, Zhao Huiying

Abstract excerpt

BACKGROUND: Observational studies have revealed that type 2 diabetes (T2D) is associated with an increased risk of peripheral artery disease (PAD). However, whether the two diseases share a genetic basis and whether the relationship is causal remain unclear. It is also unclear as to whether these relationships differ between ethnic groups. METHODS: By leveraging large-scale genome-wide association study (GWAS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36042491
DOI: 10.1186/s12916-022-02476-0
PMCID: PMC9429730

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