Article
Mutational spectrum for guiding the decision of adjuvant treatment in patients with resected biliary tract carcinoma.
Cancer medicine - 1 Aug 2023
Li Yunfeng, Tan Chaochao, Yin Xinmin, Zhu Siwei, Cai Rongyao, Liao Chunhong, Wu Yifei, Zeng Qihong, Cai Chengzhi, Xie Wang, He Xiangyu, Wen Hao-Quan, Lin Guomin, He Qingqing, He Tingting, Gu Peng, Liu Chang-Jun
Abstract excerpt
BACKGROUND: Systemic chemotherapy or chemoradiation therapy has proven to be effective in treating advanced biliary tract carcinoma (BTC). However, its efficacy in the adjuvant setting remains controversial. Therefore, this study aimed to determine the prognostic significance of genomic biomarkers in resected BTC and their potential role in stratifying patients for adjuvant treatment. METHODS: We retrospectively...
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