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CHI3L1 induces autophagy through the JNK pathway in lung cancer cells

20 Jun 2023

Abstract excerpt

CHI3L1 is closely related to the molecular mechanisms of cancer cell migration, growth, and death. According to recent research, autophagy regulates tumor growth during various stages of cancer development. This study examined the association between CHI3L1 and autophagy in human lung cancer cells. In CHI3L1-overexpressing lung cancer cells, the expression of LC3, an autophagosome marker, and the accumulation of...

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PMID: 37340009
DOI: 10.1038/s41598-023-36844-4

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