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Article

PINK1 Overexpression Promotes Cell Migration and Proliferation via Regulation of Autophagy and Predicts a Poor Prognosis in Lung Cancer Cases

1 Aug 2020

Abstract excerpt

Background: Lung cancer remains the leading cause of cancer-related death worldwide. The human PINK1 gene (PTEN induced kinase 1, Park6), an important gene for Parkinson’s disease, was found to be associated with tumor development although the molecular mechanisms underlying this relationship remain largely unknown. Objective: To analyze the clinical value and molecular mechanism of PINK1 in non-small cell lung...

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PMID: 32904694
DOI: 10.2147/cmar.s262466

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