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Article

Enhancing the organic solvent resistance of ω-amine transaminase for enantioselective synthesis of (R)-(+)-1(1-naphthyl)-ethylamine.

Biotechnology journal - 1 Oct 2023

Wang Chun-Ning, Qiu Shuai, Fan Fang-Fang, Lyu Chang-Jiang, Hu Sheng, Zhao Wei-Rui, Mei Jia-Qi, Mei Le-He, Huang Jun

Abstract excerpt

BACKGROUND: Biocatalysis in high-concentration organic solvents has been applied to produce various industrial products with many advantages. However, using enzymes in organic solvents often suffers from inactivation or decreased catalytic activity and stability. An R-selective ω-amine transaminase from Aspergillus terreus (AtATA) exhibited activity toward 1-acetylnaphthalene. However, AtATA displayed...

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Aspergillus
Dimethyl Sulfoxide
Enzyme Stability
Fungal Proteins
Naphthalenes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stereoisomerism

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PMID: 37337619
DOI: 10.1002/biot.202300120

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