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Article

The ERBB2 Exonic Variant Pro1170Ala Modulates Mitogen-Activated Protein Kinase Signaling Cascades and Associates with Allergic Asthma.

International archives of allergy and immunology - 1 Jan 2023

Sio Yang Yie, Gan Wei Liang, Ng Wing Shan, Matta Sri Anusha, Say Yee-How, Teh Keng Foo, Wong Yi Ru, Rawanan Shah Smyrna Moti, Reginald Kavita, Chew Fook Tim

Abstract excerpt

INTRODUCTION: Previous studies have indicated the ERBB2 genetic variants in the 17q12 locus might be associated with asthma; however, the functional effects of these variants on asthma risk remain inconclusive. This study aimed to characterize the functional roles of asthma-associated ERBB2 single nucleotide polymorphisms (SNPs) in asthma pathogenesis by performing genetic association and functional analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptor, ErbB-2

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Source

Identifiers

PMID: 37336194
DOI: 10.1159/000530960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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