Article
Gene polymorphism of epidermal growth factor receptor and airway hyperresponsiveness in young allergic subjects without respiratory symptoms.
Medical science monitor : international medical journal of experimental and clinical research - 1 Apr 2010
Yoshikawa Takahiro, Kanazawa Hiroshi, Tanaka Junji, Fujimoto Shigeo, Yamamoto Takushi
Abstract excerpt
BACKGROUND: Airway hyperresponsiveness (AHR) in young asymptomatic adults with atopy can be one of indicators of future symptomatic asthma. We aimed to investigate genetic association of epidermal growth factor receptor (EGFR) with the asymptomatic AHR. MATERIAL/METHODS: We recruited one-hundred and eighty-nine allergic volunteers (mean age 19.5+/-1.4 y.o.) without history of respiratory symptoms, measured...
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