Article
Sequence Similarity among Structural Repeats in the Piezo Family of Mechanosensitive Ion Channels.
Microbial physiology - 1 Jan 2023
Hendargo Kevin J, Patel Ashay O, Chukwudozie Onyeka S, Moreno-Hagelsieb Gabriel, Christen J Andres, Medrano-Soto Arturo, Saier Milton H
Abstract excerpt
Members of the Piezo family of mechanically activated cation channels are involved in multiple physiological processes in higher eukaryotes, including vascular development, cell differentiation, touch perception, hearing, and more, but they are also common in single-celled eukaryotic microorganisms. Mutations in these proteins in humans are associated with a variety of diseases, such as colorectal adenomatous...
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