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Article

Structure, kinetic properties and biological function of mechanosensitive Piezo channels

9 Jan 2021

Abstract excerpt

Mechanotransduction couples mechanical stimulation with ion flux, which is critical for normal biological processes involved in neuronal cell development, pain sensation, and red blood cell volume regulation. Although they are key mechanotransducers, mechanosensitive ion channels in mammals have remained difficult to identify. In 2010, Coste and colleagues revealed a novel family of mechanically activated cation...

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PMID: 33422128
DOI: 10.1186/s13578-020-00522-z

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