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Article

Structural fold and binding sites of the human Na⁺-phosphate cotransporter NaPi-II.

Biophysical journal - 18 Mar 2014

Fenollar-Ferrer Cristina, Patti Monica, Knöpfel Thomas, Werner Andreas, Forster Ian C, Forrest Lucy R

Abstract excerpt

Phosphate plays essential biological roles and its plasma level in humans requires tight control to avoid bone loss (insufficiency) or vascular calcification (excess). Intestinal absorption and renal reabsorption of phosphate are mediated by members of the SLC34 family of sodium-coupled transporters (NaPi-IIa,b,c) whose membrane expression is regulated by various hormones, circulating proteins, and phosphate...

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Identifiers

PMID: 24655502
DOI: 10.1016/j.bpj.2014.01.043
PMCID: PMC3984976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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