Article
A pangenome reference of 36 Chinese populations.
Nature - 1 Jul 2023
Gao Yang, Yang Xiaofei, Chen Hao, Tan Xinjiang, Yang Zhaoqing, Deng Lian, Wang Baonan, Kong Shuang, Li Songyang, Cui Yuhang, Lei Chang, Wang Yimin, Pan Yuwen, Ma Sen, Sun Hao, Zhao Xiaohan, Shi Yingbing, Yang Ziyi, Wu Dongdong, Wu Shaoyuan, Zhao Xingming, Shi Binyin, Jin Li, Hu Zhibin, Lu Yan, Chu Jiayou, Ye Kai, Xu Shuhua
Abstract excerpt
Human genomics is witnessing an ongoing paradigm shift from a single reference sequence to a pangenome form, but populations of Asian ancestry are underrepresented. Here we present data from the first phase of the Chinese Pangenome Consortium, including a collection of 116 high-quality and haplotype-phased de novo assemblies based on 58 core samples representing 36 minority Chinese ethnic groups. With an average...
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