Article
A global reference for human genetic variation.
Nature - 1 Oct 2015
Auton Adam, Brooks Lisa D, Durbin Richard M, Garrison Erik P, Kang Hyun Min, Korbel Jan O, Marchini Jonathan L, McCarthy Shane, McVean Gil A, Abecasis Gonçalo R
Abstract excerpt
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-genome sequencing, deep exome sequencing, and dense...
Topics
- Datasets as Topic
- Demography
- Disease Susceptibility
- Exome
- Genetic Variation
- Genetics, Medical
- Genetics, Population
- Genome, Human
- Genome-Wide Association Study
- Genomics
- Genotype