Deep whole-genome sequencing of 90 Han Chinese genomes.

Abstract excerpt

Next-generation sequencing provides a high-resolution insight into human genetic information. However, the focus of previous studies has primarily been on low-coverage data due to the high cost of sequencing. Although the 1000 Genomes Project and the Haplotype Reference Consortium have both provided powerful reference panels for imputation, low-frequency and novel variants remain difficult to discover and call...

Topics

Join the communities discussing this publication.

• Asian People
• Gene Frequency
• Genome, Human
• High-Throughput Nucleotide Sequencing
• INDEL Mutation