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Construction and Applications of Mammalian Cell-Based DNA-Encoded Peptide/Protein Libraries

14 Jun 2023

Abstract excerpt

DNA-encoded peptide/protein libraries are the starting point for protein evolutionary modification and functional peptide/antibody selection. Different display technologies, protein directed evolution, and deep mutational scanning (DMS) experiments employ DNA-encoded libraries to provide sequence variations for downstream affinity- or function-based selections. Mammalian cells promise the inherent...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 37315219
DOI: 10.1021/acssynbio.3c00043

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