Article

Generation of monoclonal antibody-producing mammalian cell lines

2013-04-01

Abstract excerpt

Clinical effectiveness has driven the commercial success of monoclonal antibody (mAb) products. Mammalian cells are currently the preferred system for large-scale production as the mAbs produced are biochemically similar to human forms. The cell line generation process is tedious and time-consuming as clones with high productivity, stable long-term expression and good product quality are rare occurrences. Cell lin...

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Literature Corpus work: d461aef5-66c1-568c-a5eb-0822a2833139
DOI: 10.4155/pbp.13.8

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