Article
Characterization of MHC class II B polymorphism in bottlenecked New Zealand saddlebacks reveals low levels of genetic diversity.
Immunogenetics - 1 Aug 2013
Sutton Jolene T, Robertson Bruce C, Grueber Catherine E, Stanton Jo-Ann L, Jamieson Ian G
Abstract excerpt
The major histocompatibility complex (MHC) is integral to the vertebrate adaptive immune system. Characterizing diversity at functional MHC genes is invaluable for elucidating patterns of adaptive variation in wild populations, and is particularly interesting in species of conservation concern, which may suffer from reduced genetic diversity and compromised disease resilience. Here, we use next generation...
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