Article
Shared evolutionary origin of major histocompatibility complex polymorphism in sympatric lemurs.
Molecular ecology - 1 Oct 2017
Kaesler Eva, Kappeler Peter M, Brameier Markus, Demeler Janina, Kraus Cornelia, Rakotoniaina Josué H, Hämäläinen Anni M, Huchard Elise
Abstract excerpt
Genes of the major histocompatibility complex (MHC) play a central role in adaptive immune responses of vertebrates. They exhibit remarkable polymorphism, often crossing species boundaries with similar alleles or allelic motifs shared across species. This pattern may reflect parallel parasite-mediated selective pressures, either favouring the long maintenance of ancestral MHC allelic lineages across successive...
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