Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial DNA methylation in metabolic associated fatty liver disease

25 May 2023

Abstract excerpt

Introduction: Hepatic lipid accumulation and mitochondrial dysfunction are hallmarks of metabolic associated fatty liver disease (MAFLD), yet molecular parameters underlying MAFLD progression are not well understood. Differential methylation within the mitochondrial DNA (mtDNA) has been suggested to be associated with dysfunctional mitochondria, also during progression to Metabolic Steatohepatitis (MeSH). This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Liver Disease Diagnosis and Treatment
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37305089
DOI: 10.3389/fnut.2023.964337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial DNA methylation in metabolic associated fatty liver diseasePMID 37305089Read ↗

Insights into the role of nucleotide methylation in metabolic-associated fatty liver diseaseSemantic proximity Read ↗

An Update in Epigenetics in Metabolic-Associated Fatty Liver DiseaseSemantic proximity Read ↗

Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylationSemantic proximity Read ↗

Integrative transcriptomic and genomic analyses unveil the IFI16 variants and expression as MASLD progression markersSemantic proximity Read ↗

Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver diseaseSemantic proximity Read ↗

Mitochondrial Dysfunction Induces Hepatic Lipid Accumulation and Inflammatory Responses in mtDNA Mutator MiceSemantic proximity Read ↗

Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins.Semantic proximity Read ↗

TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in <i>in vitro</i> modelsSemantic proximity Read ↗

Association Between Active DNA Demethylation and Liver Fibrosis in Individuals with Metabolic‐ Associated Steatotic Liver Disease (MASLD)Semantic proximity Read ↗

Perturbation of TM6SF2 Expression Alters Lipid Metabolism in a Human Liver Cell Line.Semantic proximity Read ↗

Loss of hepatic Mboat7 leads to liver fibrosis.Semantic proximity Read ↗

Association Between Active DNA Demethylation and Liver Fibrosis in Individuals with Metabolic-Associated Steatotic Liver Disease (MASLD)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.