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Article

PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells

1 Jan 2021

Abstract excerpt

Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin (CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various tumors. However, a significant percentage of cancer patients are resistant to CDDP treatment. Due to the CDDP side effects on normal tissues, the diagnosis of CDDP resistance is required to suggest the most efficient therapeutic...

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PMID: 37303943
DOI: 10.32604/or.2022.025323

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