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Transcriptome profiling of cervical cancer cells acquired resistance to cisplatin by deep sequencing

11 Jul 2019

Abstract excerpt

Cervical cancer is one of the most fatal malignancies in females. Acquired resistance to chemotherapeutic agent is one reason behind this lethality. In this study, we developed cisplatin resistance cell line, subsequently examined the molecular mechanisms linked. Transcriptome sequencing technology was utilized to compare the various expression models between the cisplatin-resistant cell line (Hela/DDP) and its...

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PMID: 31293179
DOI: 10.1080/21691401.2019.1637882

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