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The Role of Macrophages in Atherosclerosis: Participants and Therapists.

Cardiovascular drugs and therapy - 1 Apr 2025

Liu Xiaoyu, Pang Shuchao, Jiang Yangyang, Wang Lixin, Liu Yi

Abstract excerpt

Currently, atherosclerosis, characterized by the dysfunction of lipid metabolism and chronic inflammation in the intimal space of the vessel, is considered to be a metabolic disease. As the most abundant innate immune cells in the body, macrophages play a key role in the onset, progression, or regression of atherosclerosis. For example, macrophages exhibit several polarization states in response to...

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PMID: 37864633
DOI: 10.1007/s10557-023-07513-5

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