Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel NUP98::ASH1L Gene Fusion in Acute Myeloid Leukemia Detected by Optical Genome Mapping

27 May 2023

Abstract excerpt

Optical genome mapping (OGM) recently has demonstrated the potential to improve genetic diagnostics in acute myeloid leukemia (AML). In this study, OGM was utilized as a tool for the detection of genome-wide structural variants and disease monitoring. A previously unrecognized NUP98::ASH1L fusion was detected in an adult patient with secondary AML. OGM identified the fusion of NUP98 to Absent, Small, or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer Genomics and Diagnostics
Share to Genomics and Chromatin Dynamics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37296904
DOI: 10.3390/cancers15112942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel NUP98::ASH1L Gene Fusion in Acute Myeloid Leukemia Detected by Optical Genome MappingPMID 37296904Read ↗

A National Multicenter Evaluation of the Clinical Utility of Optical Genome Mapping for Assessment of Genomic Aberrations in Acute Myeloid LeukemiaSemantic proximity Read ↗

Application of Optical Genome Mapping for the Diagnosis and Risk Stratification of Myeloid and Lymphoid MalignanciesSemantic proximity Read ↗

Optical Genome Mapping for Cytogenetic Diagnostics in AMLSemantic proximity Read ↗

Genomic structural variants analysis in leukemia by a novel cytogenetic technique: Optical genome mappingSemantic proximity Read ↗

Optical genome mapping improves the accuracy of classification, risk stratification, and personalized treatment strategies for patients with acute myeloid leukemiaSemantic proximity Read ↗

Application of Optical Genome Mapping to the Risk Stratification and Treatment Optimization of Hematologic DiseasesSemantic proximity Read ↗

Optical genome mapping in acute myeloid leukemia: a multicenter evaluationSemantic proximity Read ↗

Optical genome mapping for structural variation analysis in hematologic malignanciesSemantic proximity Read ↗

Optical genome mapping reveals additional prognostic information compared to conventional cytogenetics in AML / MDS patientsSemantic proximity Read ↗

Feasibility of Optical Genome Mapping in Cytogenetic Diagnostics of Hematological Neoplasms: A New Way to Look at DNASemantic proximity Read ↗

Optical genome mapping refines cytogenetic diagnostics, prognostic stratification and provides new molecular insights in adult MDS/AML patientsSemantic proximity Read ↗

Structural Variant Analysis of Complex Karyotype Myelodysplastic Neoplasia Through Optical Genome MappingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.