Article

Application of Optical Genome Mapping to the Risk Stratification and Treatment Optimization of Hematologic Diseases

2024-02-23

Abstract excerpt

Structural variations (SVs) play a key role in the pathogenicity of hematological malignancies. Optical genome mapping (OGM) is an emerging technology that enables genome-wide detection of all classes of SVs at a high resolution and sensitivity. Identification of cryptic SVs leading to gene disruption or predicted novel gene fusions could be important drivers for cancer development and/or portend a prognostic rele...

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Literature Corpus work: 8584321f-0ddc-5e6c-935c-27f92492d535
DOI: 10.20944/preprints202402.1332.v1

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