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Optical genome mapping reveals additional prognostic information compared to conventional cytogenetics in AML / MDS patients

22 Jan 2022

Abstract excerpt

Cytogenetic diagnostics play a crucial role in risk stratification and classification of myeloid malignancies such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), thus influencing treatment decisions. Optical genome mapping (OGM) is a novel whole genome method for the detection of cytogenetic abnormalities. Our study assessed the applicability and practicality of OGM as diagnostic tool in AML...

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PMID: 35064925
DOI: 10.1002/ijc.33942

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