Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Application of Optical Genome Mapping for the Diagnosis and Risk Stratification of Myeloid and Lymphoid Malignancies

16 Jun 2025

Abstract excerpt

Optical genome mapping (OGM) is a novel, high-resolution technology for genome-wide detection of structural variants, offering clear advantages over conventional cytogenetics in hematologic malignancies. We applied OGM to a large cohort of patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDSs), and B-cell acute lymphoblastic leukemia (B-ALL) to evaluate its clinical utility. In AML and MDS,...

Topics

Join the communities discussing this publication.

Acute Myeloid Leukemia Research
Chronic Lymphocytic Leukemia Research
Lymphoma Diagnosis and Treatment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40565225
DOI: 10.3390/ijms26125763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Application of Optical Genome Mapping for the Diagnosis and Risk Stratification of Myeloid and Lymphoid MalignanciesPMID 40565225Read ↗

Optical genome mapping improves the accuracy of classification, risk stratification, and personalized treatment strategies for patients with acute myeloid leukemiaSemantic proximity Read ↗

Feasibility of Optical Genome Mapping in Cytogenetic Diagnostics of Hematological Neoplasms: A New Way to Look at DNASemantic proximity Read ↗

A National Multicenter Evaluation of the Clinical Utility of Optical Genome Mapping for Assessment of Genomic Aberrations in Acute Myeloid LeukemiaSemantic proximity Read ↗

Genomic structural variants analysis in leukemia by a novel cytogenetic technique: Optical genome mappingSemantic proximity Read ↗

Optical Genome Mapping for Cytogenetic Diagnostics in AMLSemantic proximity Read ↗

Structural Variant Analysis of Complex Karyotype Myelodysplastic Neoplasia Through Optical Genome MappingSemantic proximity Read ↗

Application of Optical Genome Mapping to the Risk Stratification and Treatment Optimization of Hematologic DiseasesSemantic proximity Read ↗

Optical genome mapping refines cytogenetic diagnostics, prognostic stratification and provides new molecular insights in adult MDS/AML patientsSemantic proximity Read ↗

Optical genome mapping in acute myeloid leukemia: a multicenter evaluationSemantic proximity Read ↗

Optical genome mapping reveals additional prognostic information compared to conventional cytogenetics in AML / MDS patientsSemantic proximity Read ↗

Clinical Utility of Optical Genome Mapping as an Additional Tool in a Standard Cytogenetic Workup in Hematological MalignanciesSemantic proximity Read ↗

Application of Optical Genome Mapping For Comprehensive Assessment of Chromosomal Structural Variants for Clinical Evaluation of Myelodysplastic SyndromesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.