Optical Genome Mapping for Cytogenetic Diagnostics in AML

doi:10.3390/cancers15061684

Article

Optical Genome Mapping for Cytogenetic Diagnostics in AML

9 Mar 2023

Abstract excerpt

The classification and risk stratification of acute myeloid leukemia (AML) is based on reliable genetic diagnostics. A broad and expanding variety of relevant aberrations are structural variants beyond single-nucleotide variants. Optical Genome Mapping is an unbiased, genome-wide, amplification-free method for the detection of structural variants. In this review, the current knowledge of Optical Genome Mapping...

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