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Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C

21 Apr 2023

Abstract excerpt

Differential host responses in coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) remain poorly characterized. Here, we use next-generation sequencing to longitudinally analyze blood samples from pediatric patients with COVID-19 or MIS-C across three hospitals. Profiling of plasma cell-free nucleic acids uncovers distinct signatures of cell injury and death between...

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PMID: 37279751
DOI: 10.1016/j.xcrm.2023.101034

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