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Article

PreCimp: Pre-collapsing imputation approach increases imputation accuracy of rare variants in terms of collapsed variables.

Genetic epidemiology - 1 Jan 2017

Kim Young Jin, Lee Juyoung, Kim Bong-Jo, Park Taesung

Abstract excerpt

Imputation is widely used for obtaining information about rare variants. However, one issue concerning imputation is the low accuracy of imputed rare variants as the inaccurate imputed rare variants may distort the results of region-based association tests. Therefore, we developed a pre-collapsing imputation method (PreCimp) to improve the accuracy of imputation by using collapsed variables. Briefly, collapsed...

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Identifiers

PMID: 27859580
DOI: 10.1002/gepi.22020
PMCID: PMC5154802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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