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Article

Mutation Burden Independently Predicts Survival in the Pan-Cancer Atlas.

JCO precision oncology - 1 Jun 2023

Smith Jeffrey R, Parl Fritz F, Dupont William D

Abstract excerpt

PURPOSE: Long-standing clinical predictors of cancer survival have included histopathologic type, stage, and grade. We hypothesized that the principal categories of tumor somatic mutations might also portend survival. We investigated this hypothesis using the Pan-Cancer Atlas, encompassing clinical, genomic, and outcome data of 10,652 patients and 32 cancer types. METHODS: We evaluated the prognostic capability...

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Identifiers

PMID: 37276492
DOI: 10.1200/PO.22.00571
PMCID: PMC10309535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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