Article
Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program.
Human genomics - 2 Jun 2023
Wendt Frank R, Pathak Gita A, Vahey Jacqueline, Qin Xuejun, Koller Dora, Cabrera-Mendoza Brenda, Haeny Angela, Harrington Kelly M, Rajeevan Nallakkandi, Duong Linh M, Levey Daniel F, De Angelis Flavio, De Lillo Antonella, Bigdeli Tim B, Pyarajan Saiju, Gaziano John Michael, Gelernter Joel, Aslan Mihaela, Provenzale Dawn, Helmer Drew A, Hauser Elizabeth R, Polimanti Renato
Abstract excerpt
BACKGROUND: The Million Veteran Program (MVP) participants represent 100 years of US history, including significant social and demographic changes over time. Our study assessed two aspects of the MVP: (i) longitudinal changes in population diversity and (ii) how these changes can be accounted for in genome-wide association studies (GWAS). To investigate these aspects, we divided MVP participants into five birth...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.