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Article

Biliary cancer: Utility of next-generation sequencing for clinical management.

Cancer - 15 Dec 2016

Javle Milind, Bekaii-Saab Tanios, Jain Apurva, Wang Ying, Kelley Robin Katie, Wang Kai, Kang Hyunseon C, Catenacci Daniel, Ali Siraj, Krishnan Sunil, Ahn Daniel, Bocobo Andrea Grace, Zuo Mingxin, Kaseb Ahmed, Miller Vincent, Stephens Philip J, Meric-Bernstam Funda, Shroff Rachna, Ross Jeffrey

Abstract excerpt

BACKGROUND: Biliary tract cancers (BTCs) typically present at an advanced stage, and systemic chemotherapy is often of limited benefit. METHODS: Hybrid capture-based comprehensive genomic profiling (CGP) was performed for 412 intrahepatic cholangiocarcinomas (IHCCAs), 57 extrahepatic cholangiocarcinomas (EHCCAs), and 85 gallbladder carcinomas (GBCAs). The mutational profile was correlated with the clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27622582
DOI: 10.1002/cncr.30254

Genes

KRAS
BTC
IDH1
ERBB2
FGFR2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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