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Article

Efficacy of Warfarin Therapy Guided by Pharmacogenetics: A Real-world Investigation Among Han Taiwanese.

Clinical therapeutics - 1 Jul 2023

Liu Ting-Yuan, Hsu Hsing-Yu, You Ying-Shu, Hsieh Yow-Wen, Lin Tzu-Ching, Peng Chun-Wei, Huang Hsin-Yi, Chang Shih-Sheng, Tsai Fuu-Jen

Abstract excerpt

PURPOSE: The anticoagulation activity of warfarin in populations with CYP2C9, VKORC1, and CYP4F2 variants differs between individuals and is correlated with poor international normalized ratio (INR) control. Pharmacogenetics-guided warfarin dosing has been successfully developed for patients with genetic variations in recent years. However, few real-world data have been used to investigate the INR and warfarin...

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PMID: 37301690
DOI: 10.1016/j.clinthera.2023.04.006

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