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Article

Altered physical phenotypes of leukemia cells that survive chemotherapy treatment.

Integrative biology : quantitative biosciences from nano to macro - 11 Apr 2023

Ly Chau, Ogana Heather, Kim Hye Na, Hurwitz Samantha, Deeds Eric J, Kim Yong-Mi, Rowat Amy C

Abstract excerpt

The recurrence of cancer following chemotherapy treatment is a major cause of death across solid and hematologic cancers. In B-cell acute lymphoblastic leukemia (B-ALL), relapse after initial chemotherapy treatment leads to poor patient outcomes. Here we test the hypothesis that chemotherapy-treated versus control B-ALL cells can be characterized based on cellular physical phenotypes. To quantify physical...

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Identifiers

PMID: 37247849
DOI: 10.1093/intbio/zyad006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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