Article
Examining Sporadic Cancer Mutations Uncovers a Set of Genes Involved in Mitochondrial Maintenance.
Genes - 29 Apr 2023
Moreno Armando, Taffet Allison, Tjahjono Elissa, Anderson Quinton L, Kirienko Natalia V
Abstract excerpt
Mitochondria are key organelles for cellular health and metabolism and the activation of programmed cell death processes. Although pathways for regulating and re-establishing mitochondrial homeostasis have been identified over the past twenty years, the consequences of disrupting genes that regulate other cellular processes, such as division and proliferation, on affecting mitochondrial function remain unclear....
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