Article
ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer.
BMC cancer - 26 May 2023
Kanai Ryo, Uehara Takeshi, Yoshizawa Takahiro, Kamakura Masato, Nakajima Tomoyuki, Kinugawa Yasuhiro, Iwaya Mai, Asaka Shiho, Kitazawa Masato, Nagaya Tadanobu, Ota Hiroyoshi
Abstract excerpt
BACKGROUND: ADP-ribosylation factor-like protein 4 C (ARL4C) is a member of the ARF small GTP-binding protein subfamily. The ARL4C gene is highly expressed in colorectal cancer (CRC). ARL4C protein promotes cell motility, invasion, and proliferation. METHODS: We investigated the characteristics of ARL4C by comparing its expression at the invasion front and relationships with clinicopathological data using...
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