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Article

C 4.4 A is associated with tumor budding and epithelial–mesenchymal transition of colorectal cancer

8 Mar 2012

Abstract excerpt

C4.4A is a glycolipid-anchored membrane protein expressed in several human malignancies. The aim of this study was to explore the association between C4.4A expression at the invasion front of colorectal cancer (CRC) and tumor budding, a putative hallmark of cell invasion of CRC. Advanced CRCs (T2-4, n = 126) had a budding count of 3.66 ± 5.66, which was significantly higher than that of T1 early CRCs (1.75 ±...

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PMID: 22404718
DOI: 10.1111/j.1349-7006.2012.02263.x

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