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A two-stage genome-wide association study identified four potential early-onset nonsmall cell lung cancer risk loci based on 26,652 participants in Chinese population.

Molecular carcinogenesis - 1 Sept 2023

Fan Jingyi, Hong Tongtong, Zhao Xiaoyu, Liang Shuang, Zhu Meng, Jiang Yue, Jin Guangfu, Hu Zhibin, Ma Hongxia, Dai Juncheng, Shen Hongbing

Abstract excerpt

Early-onset lung cancer is rare with an increasing incidence rate. Although several genetic variants have been identified for it with candidate gene approaches, no genome-wide association study (GWAS) has been reported. In this study, a two-stage strategy was adopted: firstly we performed a GWAS to identify variants associated with early-onset nonsmall-cell lung cancer (NSCLC) risk using 2556 cases (age ≤ 50...

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PMID: 37232355
DOI: 10.1002/mc.23561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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