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Article

Microsatellite Status Detection of Colorectal Cancer: Evaluation of Inconsistency between PCR and IHC

1 Jan 2023

Abstract excerpt

Objective: An essential component of precision medical treatment for colorectal cancer (CRC) is the use of microsatellite state in combination with polymerase chain reaction (PCR) and immunohistochemistry (IHC) as the primary clinical detection methods. Microsatellite instability-high (MSI-H) or mismatch-repair deficiency (dMMR) accounts for about 15% of all CRC patients. Characterized by a high mutation burden,...

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PMID: 37215453
DOI: 10.7150/jca.81675

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