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Article

The relationship between clinical phenotype and kallikrein-kinin bioregulation in different forms of arthritis.

BMC musculoskeletal disorders - 18 May 2023

Tan Dino B A, Tedja Chantalia, Kuster Lukas, Raymond Warren D, Harsanyi Andreea, Chowalloor Priya V, Misso Neil L, Argawal Shashi, Bhoola Kanti D, Keen Helen I

Abstract excerpt

OBJECTIVE: Patients with rheumatoid arthritis (RA) have shown increased levels of neutrophils generating kallikrein-kinin peptides in blood which are potent mediators of inflammation. This study investigated the association between the bioregulation of kinin-mediated inflammation with the clinical, quality of life, and imaging characteristics (e.g. ultrasonography) of different arthritides. METHODS: Patients with...

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Source

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Identifiers

PMID: 37202736
DOI: 10.1186/s12891-023-06388-9
PMCID: PMC10193675

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