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Article

Viral Capsid, Antibody, and Receptor Interactions: Experimental Analysis of the Antibody Escape Evolution of Canine Parvovirus.

Journal of virology - 29 Jun 2023

López-Astacio Robert A, Adu Oluwafemi F, Goetschius Daniel J, Lee Hyunwook, Weichert Wendy S, Wasik Brian R, Frueh Simon P, Alford Brynn K, Voorhees Ian E H, Flint Joseph F, Saddoris Sarah, Goodman Laura B, Holmes Edward C, Hafenstein Susan L, Parrish Colin R

Abstract excerpt

Canine parvovirus (CPV) is a small nonenveloped single-stranded DNA virus that causes serious diseases in dogs worldwide. The original strain of the virus (CPV-2) emerged in dogs during the late 1970s due to a host range switch of a virus similar to the feline panleukopenia virus that infected another host. The virus that emerged in dogs had altered capsid receptor and antibody binding sites, with some changes...

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Identifiers

PMID: 37199627
DOI: 10.1128/jvi.00090-23
PMCID: PMC10308881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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