Article
The role of evolutionary intermediates in the host adaptation of canine parvovirus.
Journal of virology - 1 Feb 2012
Stucker Karla M, Pagan Israel, Cifuente Javier O, Kaelber Jason T, Lillie Tyler D, Hafenstein Susan, Holmes Edward C, Parrish Colin R
Abstract excerpt
The adaptation of viruses to new hosts is a poorly understood process likely involving a variety of viral structures and functions that allow efficient replication and spread. Canine parvovirus (CPV) emerged in the late 1970s as a host-range variant of a virus related to feline panleukopenia virus (FPV). Within a few years of its emergence in dogs, there was a worldwide replacement of the initial virus strain...
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