Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glycoprotein acetyls and depression: Testing for directionality and potential causality using longitudinal data and Mendelian randomization analyses.

Journal of affective disorders - 15 Aug 2023

Crick Daisy C P, Sanderson Eleanor, Jones Hannah, Goulding Neil, Borges Maria Carolina, Clayton Gemma, Carter Alice R, Halligan Sarah, Lawlor Deborah A, Khandaker Golam M, Fraser Abigail

Abstract excerpt

BACKGROUND: Inflammation is associated with depression, but causality remains unclear. We investigated potential causality and direction of effect between inflammation and depression. METHODS: Using data from the ALSPAC birth cohort (n = 4021; 42.18 % male), we used multivariable regression to investigate bidirectional longitudinal associations of GlycA and depression and depression symptoms, assessed at ages 18y...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Causality
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Genome-Wide Association Study

Share to Inflammation

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37196932
DOI: 10.1016/j.jad.2023.05.033
PMCID: PMC7615476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glycoprotein acetyls and depression: Testing for directionality and potential causality using longitudinal data and Mendelian randomization analyses.PMID 37196932Read ↗

Body Mass Index And Inflammation In Depression And Treatment-Resistant Depression: A Mendelian Randomization StudySemantic proximity Read ↗

Clustering of major depressive disorder genetic instruments identifies distinct and directionally opposing effects on cardiometabolic riskSemantic proximity Read ↗

Role of Inflammation in Depression and Anxiety: Tests for Disorder Specificity, Linearity and Potential Causality of Association in the UK BiobankSemantic proximity Read ↗

Association between serum apolipoprotein B and depression: A cross-sectional and Mendelian randomization analysis study.Semantic proximity Read ↗

Effects of metabolic factors in mediating the relationship between Type 2 diabetes and depression in East Asian populations: A two-step, two-sample Mendelian randomization study.Semantic proximity Read ↗

Bi-directional Mendelian randomization and multi-phenotype GWAS show causality and shared pathophysiology between depression and type 2 diabetesSemantic proximity Read ↗

Bidirectional causal relationship between depression and Type 2 diabetes: a multi-ancestry and sex stratified Mendelian Randomization analysisSemantic proximity Read ↗

Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation.Semantic proximity Read ↗

Role of Inflammation in Depressive and Anxiety Disorders, Affect, and Cognition: Genetic and Non-Genetic Findings in the Lifelines Cohort Study.Semantic proximity Read ↗

The association between depression and metabolic syndrome and its components: a bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

Beyond the resistance: how novel neurobiological understandings of depression may lead to advanced treatment strategies.Semantic proximity Read ↗

Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.