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Article

Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation.

Scientific reports - 3 Sept 2022

Galan D, Perry B I, Warrier V, Davidson C C, Stupart O, Easton D, Khandaker G M, Murray G K

Abstract excerpt

Smoking, inflammation and depression commonly co-occur and may be mechanistically linked. However, key questions remain around the direction of association and the influence of residual confounding. We aimed to characterize the association between lifetime smoking and depression, as well as to assess the role that genetically-predicted C-reactive protein (CRP) level, (an archetypal generalized inflammatory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36057695
DOI: 10.1038/s41598-022-19214-4
PMCID: PMC9440889

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