Article
Looking for RET alterations in thyroid cancer: clinical relevance, methodology and timing.
Endocrine - 1 Aug 2023
Elisei Rossella, Romei Cristina
Abstract excerpt
PURPOSE: Thyroid carcinoma (TC) is a rare neoplasia of the endocrine system and account for about 2-3% of all human tumors. According to their cell origin and histological features, different histotypes of thyroid carcinoma are described. Genetic alterations involved in the pathogenesis of thyroid cancer have been described and it has been shown that alterations of the RET gene are common events in all TC...
Topics
- Humans
- Carcinoma, Medullary
- Clinical Relevance
- Multiple Endocrine Neoplasia Type 2a
- Proto-Oncogene Proteins c-ret
- Proto-Oncogene Mas
- Thyroid Neoplasms
- Mutation
