Article
[Molecular medicine in thyroid surgery].
Chirurgia italiana - 1 Jan 2000
Moretti Sonia, Barbi Flavia, Tavano Maria, Calzolari Filippo, Misso Claudia, Lucchini Roberta, Monacelli Massimo, D'Ajello Michele, Puxeddu Efisio, Avenia Nicola
Abstract excerpt
Cancer originates from a single cell which, through the acquisition of mutations in genes for key growth and survival factors, undergoes clonal expansion. Study of the genome allowed the detection of genes whose mutation is involved in tumour formation. In detail, in most thyroid neoplasms we are now able to identify the genes which cause cancer initiation. Moreover, correlations between mutations and...
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