Article
Molecular Alterations in Thyroid Carcinoma.
Surgical pathology clinics - 1 Dec 2019
Haroon Al Rasheed Mohamed Rizwan, Xu Bin
Abstract excerpt
Thyroid carcinoma is the most common cancer in the endocrine system. Recent advances, using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid cancer. Constitutional activation of the mitogen-activated protein kinase pathway through RAS mutation, BRAF mutation, and/or fusions involving receptor tyrosine kinase (eg, (REarranged during Transfection) RET-PTC) plays a central role in...
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