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Polymorphism of Metallothionein 2A Modifies Lead Body Burden in Workers Chronically Exposed to the Metal.

Public health genomics - 1 Jan 2016

Fernandes Kelly Christine Marques, Martins Airton Cunha, Oliveira Andréia Ávila Soares de, Antunes Lusânia Maria Greggi, Cólus Ilce Mara de Syllos, Barbosa Fernando, Barcelos Gustavo Rafael Mazzaron

Abstract excerpt

Lead (Pb) is a metal that accumulates in the human body, inducing several adverse health effects. One of the proteins responsible for the distribution of metal in the body is metallothionein (MT), which is expressed by different genes, and it is supposed that genetic variation in the genes that encode MTs may affect the Pb body burden. The present study aimed to evaluate the genetic effects of the polymorphism of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 26594907
DOI: 10.1159/000441713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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