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Colorectal Cancer: Pathogenesis and Targeted Therapy

1 Mar 2025

Abstract excerpt

Colorectal cancer (CRC) ranks among the most prevalent malignant neoplasms globally. A growing body of evidence underscores the pivotal roles of genetic alterations and dysregulated epigenetic modifications in the pathogenesis of CRC. In recent years, the reprogramming of tumor cell metabolism has been increasingly acknowledged as a hallmark of cancer. Substantial evidence suggests a crosstalk between tumor cell...

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PMID: 40060193
DOI: 10.1002/mco2.70127

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